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Peptide therapy is a form of treatment that uses short chain of amino acids called peptide to give therapeutic effects by targeting multiple systems in the body. Human Growth Hormone (HGH) secretagogue is a type of peptide that helps increase growth hormone levels more naturally as compared to recombinant HGH (rhGH).
HGH is an important hormone that should not be passed by anyone who is interested in living longer and healthier life. It’s know as the repair hormone and plays a key role in the maintenance of a youthful appearance and healthy bodily functions. HGH also keeps you in a better mood, normalizes weight by increasing muscle mass and decreasing fat, gives you more energy, and helps you to think clearly.
Just like testosterone, HGH decreases beginning at age thirty. As we age, most of us in the have levels of HGH that are too low for optimal health. Without HGH, the body lack its ability to repair itself properly and goes downhill health-wise. Because of the high cost ($1,000-$2,000 per month) and strict legal environment surrounding the prescription of HGH, Alpha Hormones® recommend using peptide therapy instead. HGH secretagogues such as Sermorelin and Tesamorelin are generally safe and effective to treat suboptimal growth hormone levels.
Sermorelin was approved by the FDA in 1997 to treat growth hormone deficiency. It’s a peptide that encourages natural production of growth hormone from the pituitary gland. Sermorelin is growth hormone releasing hormone (GHRH) and is actually a peptide with the first 29 amino acids of growth hormone. This is why Sermorelin causes growth hormone to be secreted from the pituitary gland and is called a secretagogue. Sermorelin works to burn fat, increase lean muscle, improve hormonal balance, enhance energy, and support the immune system by stimulating the production and release of hormones by the pituitary. While Sermorelin is not as powerful as supplementing extra growth hormone, it is a healthier alternative than HGH since it encourages natural and healthy pituitary function.The benefits of HGH secretagogue go far beyond encouraging weight loss and enhancing lean muscle mass.
CJC-1295 stimulates growth hormone secretion and will keep a steady increase of HGH and IGF-1 with no increase in prolactin, leading to fat loss, and increased protein synthesis, in turn promoting growth. CJC-1295 is a tetrasubstituted 29-amino acid peptide hormone, primarily functioning as a growth hormone releasing hormone (GHRH) analog. CJC-1295 performs better than the Sermorelin. It accomplishes this by using protecting groups around the amino acids of GHRH typically susceptible to enzymatic degradation, thus increasing the half-life. Unlike Sermorelin, CJC-1295 was not FDA approved.
Ipamorelin is a selective GH-Secretagogue and ghrelin receptor agonist. It was developed by Novo Nordisk and was FDA approved for Postoperative Ileus but was then discontinued. The potency of ghrelin stimulation can be compared to GHRP6 with less appetite stimulation properties. However, unlike other GH-Secretagogues this pentapeptide doesn’t release the same volumes of cortisol, acetylcholine, prolactin and aldosterone. For this reason, Ipamorelin has been considered the first selective GH which promotes secretion. It’s important to note that CJC-1295 and Ipamorelin are available for clinical usage but they’re still considered as research and developmental drugs.
Consequently CJC-1295 without DAC (Drug Affinity Complex) is designed to provide a GHRH-like stimulation around the clock with increased amplitude and longer stimulation, (28 minutes instead of 8-12 minutes of Sermorelin), maintaining the natural pulsatile stimulation of the pituitary without decreasing secretion as observed in CJC-1295 with DAC.
Tesamorelin is another FDA approved HGH secretagogue sold under the brand name Egrifta. It is a growth hormone releasing factor (GRF) analog indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. GRF is a hypothalamic peptide that acts on the pituitary somatotroph cells to stimulate the synthesis and pulsatile release of endogenous growth hormone, which is both anabolic and lipolytic. Tesamorelin is currently the most effective HGH secretagogue in the market that is proven to increase IGF-1 levels and reduce visceral fat.
Enjoy a better night’s sleep, less daytime fatigue, enhance mental clarity, significantly improved skin appearance while receiving an enhanced synergistic boost to Insulin-like Growth Factor-1 (IGF-1) with HGH secretagogues. Alpha Hormones medical providers will review your health questionnaire, medical history, and lab results to understand your overall health and make the appropriate recommendation that suits your medical needs, challenges, and goals.
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